Hello there, 100+ sheet does look like a lot. Every pro/e seller will tell you there is not limit for pro/e, that you can manage files as large as you may imagine. But when you talk to serious ptc tech support, they sometimes suggest that drawings with 10 sheets are already too large (I've been there) What is true, is that pro/e requires a vast amount of memory and hardware resources to succesfully manage a file that big, as it needs to upload the models, reps, bom, tables, etc. It could probably cause you a crash. Check the xtop.exe file at the task manager, and see how much memory is demanding, if you are reaching 1500 or so, its too much and you may consider eather splinting your file (though you'll need to erase the models no longer present in the sheets you erased), or moving to a 64 bit platform with grater RAM and let pro/e use it at large.